Dr. Arthur Epstein, O.D., F.A.A.O., finds the emerging resistance of bacteria to antibiotics one of the most alarming problems in medicine. Recent data showing increased resistance in virulent ocular pathogens like Pseudomonas underscore the need for caution and prudence in treating ocular infections, he warns. When sight is at risk, do the following:

• Take cultures and if necessary, modify antibiotic selection by sensitivity results.

• Use appropriately selected antibiotics to increase the therapeutic effect and simultaneously reduce the likelihood of resistant organisms developing.

• When empiric treatment is necessary, initiate broad-spectrum multi-agent therapy.